D86H (p.Asp86His) variant of CCND3 (G1/S-specific cyclin-D3)
D86H (p.Asp86His) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
D86H (p.Asp86His) variant details
- p.Asp86His
- ExAC rs745309717
- gnomAD rs745309717
- Missense
- Variant Prioritization Score for Impact Estimate 0.761
- REVEL 0.73
- CADD 28.70
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available