C91R (p.Cys91Arg) variant of CCND3 (G1/S-specific cyclin-D3)
C91R (p.Cys91Arg) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
C91R (p.Cys91Arg) variant details
- p.Cys91Arg
- ExAC rs758116591
- gnomAD rs758116591
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.07
- CADD 21.00
- PolyPhen-2 0.24
- SIFT 0.22
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available