C125* (p.Cys125Ter) variant of CCND3 (G1/S-specific cyclin-D3)
C125* (p.Cys125Ter) in CCND3 (G1/S-specific cyclin-D3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
C125* (p.Cys125Ter) variant details
- p.Cys125Ter
- gnomAD 6-41936070-G-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.18
- CADD 25.40
- PolyPhen-2 0.46
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available