A81S (p.Ala81Ser) variant of CCND3 (G1/S-specific cyclin-D3)
A81S (p.Ala81Ser) in CCND3 (G1/S-specific cyclin-D3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
A81S (p.Ala81Ser) variant details
- p.Ala81Ser
- gnomAD rs1385705873
- Missense
- Variant Prioritization Score for Impact Estimate 0.436
- REVEL 0.21
- CADD 23.00
- PolyPhen-2 0.14
- SIFT 0.21
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available