Y54C (p.Tyr54Cys) variant of CCND2 (G1/S-specific cyclin-D2)
Y54C (p.Tyr54Cys) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
Y54C (p.Tyr54Cys) variant details
- p.Tyr54Cys
- gnomAD 12-4274201-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.10
- CADD 23.10
- PolyPhen-2 0.03
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available