Y37H (p.Tyr37His) variant of CCND2 (G1/S-specific cyclin-D2)
Y37H (p.Tyr37His) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
Y37H (p.Tyr37His) variant details
- p.Tyr37His
- ExAC rs746820501
- gnomAD rs746820501
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.20
- MetaLR 0.06
- MetaSVM -1.11
- CADD 26.90
- PolyPhen-2 0.52
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available