V8M (p.Val8Met) variant of CCND2 (G1/S-specific cyclin-D2)
V8M (p.Val8Met) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
V8M (p.Val8Met) variant details
- p.Val8Met
- ESP rs370617608
- ExAC rs370617608
- TOPMed rs370617608
- gnomAD rs370617608
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.09
- MetaLR 0.02
- MetaSVM -1.03
- CADD 22.80
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available