V15M (p.Val15Met) variant of CCND2 (G1/S-specific cyclin-D2)
V15M (p.Val15Met) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V15M (p.Val15Met) variant details
- p.Val15Met
- gnomAD rs1374736402
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.10
- MetaLR 0.01
- MetaSVM -0.97
- CADD 23.20
- PolyPhen-2 0.05
- SIFT 0.17
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available