V15A (p.Val15Ala) variant of CCND2 (G1/S-specific cyclin-D2)
V15A (p.Val15Ala) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V15A (p.Val15Ala) variant details
- p.Val15Ala
- gnomAD rs1242864601
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.11
- MetaLR 0.01
- MetaSVM -1.01
- CADD 22.90
- PolyPhen-2 0.01
- SIFT 0.40
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available