R57T (p.Arg57Thr) variant of CCND2 (G1/S-specific cyclin-D2)
R57T (p.Arg57Thr) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R57T (p.Arg57Thr) variant details
- p.Arg57Thr
- gnomAD rs1863828145
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.22
- MetaLR 0.03
- MetaSVM -1.04
- CADD 29.30
- PolyPhen-2 0.40
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available