R57G (p.Arg57Gly) variant of CCND2 (G1/S-specific cyclin-D2)
R57G (p.Arg57Gly) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
R57G (p.Arg57Gly) variant details
- p.Arg57Gly
- TOPMed rs61731957
- gnomAD rs61731957
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.33
- MetaLR 0.02
- MetaSVM -0.99
- CADD 32.00
- PolyPhen-2 0.07
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available