R16W (p.Arg16Trp) variant of CCND2 (G1/S-specific cyclin-D2)
R16W (p.Arg16Trp) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
R16W (p.Arg16Trp) variant details
- p.Arg16Trp
- ExAC rs750148470
- TOPMed rs750148470
- gnomAD rs750148470
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.10
- MetaLR 0.02
- MetaSVM -0.99
- CADD 26.60
- PolyPhen-2 0.15
- SIFT 0.01
- Population evidence available
- Structural context available