N19S (p.Asn19Ser) variant of CCND2 (G1/S-specific cyclin-D2)
N19S (p.Asn19Ser) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
N19S (p.Asn19Ser) variant details
- p.Asn19Ser
- gnomAD 12-4274096-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.11
- MetaLR 0.02
- MetaSVM -1.02
- CADD 18.10
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available
- Literature evidence available