M58V (p.Met58Val) variant of CCND2 (G1/S-specific cyclin-D2)
M58V (p.Met58Val) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
M58V (p.Met58Val) variant details
- p.Met58Val
- gnomAD 12-4274212-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.27
- CADD 23.10
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available