M58T (p.Met58Thr) variant of CCND2 (G1/S-specific cyclin-D2)
M58T (p.Met58Thr) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
M58T (p.Met58Thr) variant details
- p.Met58Thr
- ExAC rs769290616
- gnomAD rs769290616
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.33
- MetaLR 0.02
- MetaSVM -1.07
- CADD 25.50
- PolyPhen-2 0.06
- SIFT 0.04
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available