L3M (p.Leu3Met) variant of CCND2 (G1/S-specific cyclin-D2)
L3M (p.Leu3Met) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
L3M (p.Leu3Met) variant details
- p.Leu3Met
- gnomAD 12-4274047-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.26
- MetaLR 0.14
- MetaSVM -0.82
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available