L31V (p.Leu31Val) variant of CCND2 (G1/S-specific cyclin-D2)
L31V (p.Leu31Val) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L31V (p.Leu31Val) variant details
- p.Leu31Val
- ExAC rs746043858
- TOPMed rs746043858
- gnomAD rs746043858
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.30
- MetaLR 0.12
- MetaSVM -0.99
- CADD 24.60
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available