L31F (p.Leu31Phe) variant of CCND2 (G1/S-specific cyclin-D2)
L31F (p.Leu31Phe) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L31F (p.Leu31Phe) variant details
- p.Leu31Phe
- ExAC rs746043858
- TOPMed rs746043858
- gnomAD rs746043858
- Missense
- Variant Prioritization Score for Impact Estimate 0.365
- REVEL 0.28
- MetaLR 0.15
- MetaSVM -0.85
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available