L21F (p.Leu21Phe) variant of CCND2 (G1/S-specific cyclin-D2)
L21F (p.Leu21Phe) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L21F (p.Leu21Phe) variant details
- p.Leu21Phe
- gnomAD 12-4274101-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.04
- CADD 24.80
- PolyPhen-2 0.02
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available