K71R (p.Lys71Arg) variant of CCND2 (G1/S-specific cyclin-D2)
K71R (p.Lys71Arg) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
K71R (p.Lys71Arg) variant details
- p.Lys71Arg
- gnomAD 12-4276021-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.08
- CADD 23.70
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available