D24E (p.Asp24Glu) variant of CCND2 (G1/S-specific cyclin-D2)
D24E (p.Asp24Glu) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
D24E (p.Asp24Glu) variant details
- p.Asp24Glu
- TOPMed rs1232891371
- gnomAD rs1232891371
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.16
- MetaLR 0.04
- MetaSVM -1.10
- CADD 23.20
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available