C67W (p.Cys67Trp) variant of CCND2 (G1/S-specific cyclin-D2)
C67W (p.Cys67Trp) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
C67W (p.Cys67Trp) variant details
- p.Cys67Trp
- gnomAD 12-4276010-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.48
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available