C41G (p.Cys41Gly) variant of CCND2 (G1/S-specific cyclin-D2)
C41G (p.Cys41Gly) in CCND2 (G1/S-specific cyclin-D2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
C41G (p.Cys41Gly) variant details
- p.Cys41Gly
- TOPMed rs1215532509
- gnomAD rs1215532509
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.15
- MetaLR 0.02
- MetaSVM -1.02
- CADD 22.90
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available