Y17C (p.Tyr17Cys) variant of CCND1 (G1/S-specific cyclin-D1)
Y17C (p.Tyr17Cys) in CCND1 (G1/S-specific cyclin-D1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
Y17C (p.Tyr17Cys) variant details
- p.Tyr17Cys
- gnomAD 11-69641363-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.24
- MetaLR 0.03
- MetaSVM -1.09
- CADD 23.80
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available