R15S (p.Arg15Ser) variant of CCND1 (G1/S-specific cyclin-D1)
R15S (p.Arg15Ser) in CCND1 (G1/S-specific cyclin-D1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
R15S (p.Arg15Ser) variant details
- p.Arg15Ser
- 1000Genomes rs557545630
- Missense
- Variant Prioritization Score for Impact Estimate 0.48
- REVEL 0.25
- CADD 27.20
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the 1KG:CDX population (allele frequency 0.0057)
- Structural context available