R14S (p.Arg14Ser) variant of CCND1 (G1/S-specific cyclin-D1)
R14S (p.Arg14Ser) in CCND1 (G1/S-specific cyclin-D1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R14S (p.Arg14Ser) variant details
- p.Arg14Ser
- gnomAD rs1372181670
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.16
- CADD 22.30
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available