E11K (p.Glu11Lys) variant of CCND1 (G1/S-specific cyclin-D1)
E11K (p.Glu11Lys) in CCND1 (G1/S-specific cyclin-D1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
E11K (p.Glu11Lys) variant details
- p.Glu11Lys
- TOPMed rs1855697005
- Missense
- Variant Prioritization Score for Impact Estimate 0.442
- REVEL 0.24
- CADD 24.00
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available