D25G (p.Asp25Gly) variant of CCND1 (G1/S-specific cyclin-D1)
D25G (p.Asp25Gly) in CCND1 (G1/S-specific cyclin-D1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
D25G (p.Asp25Gly) variant details
- p.Asp25Gly
- gnomAD rs1400812649
- Missense
- Variant Prioritization Score for Impact Estimate 0.475
- REVEL 0.33
- CADD 32.00
- PolyPhen-2 0.76
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available