C8Y (p.Cys8Tyr) variant of CCND1 (G1/S-specific cyclin-D1)
C8Y (p.Cys8Tyr) in CCND1 (G1/S-specific cyclin-D1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
C8Y (p.Cys8Tyr) variant details
- p.Cys8Tyr
- cosmic curated COSV10809
- TOPMed rs1340132260
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- REVEL 0.35
- CADD 25.50
- PolyPhen-2 0.71
- SIFT 0.08
- Population evidence available
- Structural context available