C7Y (p.Cys7Tyr) variant of CCND1 (G1/S-specific cyclin-D1)
C7Y (p.Cys7Tyr) in CCND1 (G1/S-specific cyclin-D1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
C7Y (p.Cys7Tyr) variant details
- p.Cys7Tyr
- gnomAD rs1486252402
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- REVEL 0.44
- CADD 29.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available