S15G (p.Ser15Gly) variant of CBL (E3 ubiquitin-protein ligase CBL)
S15G (p.Ser15Gly) in CBL (E3 ubiquitin-protein ligase CBL) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S15G (p.Ser15Gly) variant details
- p.Ser15Gly
- gnomAD 11-119206460-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.13
- CADD 14.00
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- CBL Ubiquitin-associated domain domainome 1.0: score -1.09
- Literature evidence available