F3F (p.Phe3Phe) variant of CASR (P41180)
F3F (p.Phe3Phe) in CASR (P41180) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
F3F (p.Phe3Phe) variant details
- p.Phe3Phe
- rs764556468
- gnomAD 3-122254198-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.212
- AlphaMissense 0.19
- MetaLR 0.24
- MetaSVM -0.84
- CADD 8.62
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available