W26R (p.Trp26Arg) variant of CASP9 (Caspase-9)
W26R (p.Trp26Arg) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
W26R (p.Trp26Arg) variant details
- p.Trp26Arg
- ExAC rs775197782
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- REVEL 0.34
- CADD 27.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available