W26L (p.Trp26Leu) variant of CASP9 (Caspase-9)
W26L (p.Trp26Leu) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
W26L (p.Trp26Leu) variant details
- p.Trp26Leu
- TOPMed rs1422012687
- gnomAD rs1422012687
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- REVEL 0.25
- CADD 24.60
- PolyPhen-2 0.97
- SIFT 0.05
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available