V110A (p.Val110Ala) variant of CASP9 (Caspase-9)
V110A (p.Val110Ala) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
V110A (p.Val110Ala) variant details
- p.Val110Ala
- ExAC rs777723580
- TOPMed rs777723580
- gnomAD rs777723580
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.08
- CADD 7.96
- PolyPhen-2 0.01
- SIFT 0.69
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available