T80I (p.Thr80Ile) variant of CASP9 (Caspase-9)
T80I (p.Thr80Ile) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
T80I (p.Thr80Ile) variant details
- p.Thr80Ile
- ExAC rs781101713
- gnomAD rs781101713
- Missense
- Variant Prioritization Score for Impact Estimate 0.584
- REVEL 0.44
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available