S99W (p.Ser99Trp) variant of CASP9 (Caspase-9)
S99W (p.Ser99Trp) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
S99W (p.Ser99Trp) variant details
- p.Ser99Trp
- ExAC rs4646008
- TOPMed rs4646008
- gnomAD rs4646008
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.10
- CADD 11.70
- PolyPhen-2 0.96
- SIFT 0.12
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available