S87L (p.Ser87Leu) variant of CASP9 (Caspase-9)
S87L (p.Ser87Leu) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
S87L (p.Ser87Leu) variant details
- p.Ser87Leu
- cosmic curated COSV61601
- 1000Genomes rs535165327
- ExAC rs535165327
- TOPMed rs535165327
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.07
- CADD 24.60
- PolyPhen-2 0.85
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available