R65G (p.Arg65Gly) variant of CASP9 (Caspase-9)
R65G (p.Arg65Gly) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
R65G (p.Arg65Gly) variant details
- p.Arg65Gly
- ExAC rs771183801
- TOPMed rs771183801
- gnomAD rs771183801
- Missense
- Variant Prioritization Score for Impact Estimate 0.623
- REVEL 0.50
- CADD 27.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available