R15W (p.Arg15Trp) variant of CASP9 (Caspase-9)
R15W (p.Arg15Trp) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
R15W (p.Arg15Trp) variant details
- p.Arg15Trp
- gnomAD rs1222863415
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.11
- CADD 23.40
- PolyPhen-2 0.96
- SIFT 0.01
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available