R15Q (p.Arg15Gln) variant of CASP9 (Caspase-9)
R15Q (p.Arg15Gln) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
R15Q (p.Arg15Gln) variant details
- p.Arg15Gln
- TOPMed rs941311543
- gnomAD rs941311543
- Missense
- Variant Prioritization Score for Impact Estimate 0.0551
- REVEL 0.03
- CADD 3.68
- PolyPhen-2 0.13
- SIFT 0.28
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available