R15P (p.Arg15Pro) variant of CASP9 (Caspase-9)
R15P (p.Arg15Pro) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
R15P (p.Arg15Pro) variant details
- p.Arg15Pro
- TOPMed rs941311543
- gnomAD rs941311543
- Missense
- Variant Prioritization Score for Impact Estimate 0.204
- REVEL 0.23
- CADD 12.90
- PolyPhen-2 0.95
- SIFT 0.12
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available