R15L (p.Arg15Leu) variant of CASP9 (Caspase-9)
R15L (p.Arg15Leu) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
R15L (p.Arg15Leu) variant details
- p.Arg15Leu
- TOPMed rs941311543
- gnomAD rs941311543
- Missense
- Variant Prioritization Score for Impact Estimate 0.0757
- REVEL 0.07
- CADD 3.96
- PolyPhen-2 0.09
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available