R11W (p.Arg11Trp) variant of CASP9 (Caspase-9)
R11W (p.Arg11Trp) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
R11W (p.Arg11Trp) variant details
- p.Arg11Trp
- TOPMed rs1710342633
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.29
- CADD 25.00
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available