R116G (p.Arg116Gly) variant of CASP9 (Caspase-9)
R116G (p.Arg116Gly) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
R116G (p.Arg116Gly) variant details
- p.Arg116Gly
- ExAC rs754102522
- TOPMed rs754102522
- gnomAD rs754102522
- Missense
- Variant Prioritization Score for Impact Estimate 0.0699
- REVEL 0.04
- CADD 6.64
- PolyPhen-2 0.03
- SIFT 0.38
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available