R10W (p.Arg10Trp) variant of CASP9 (Caspase-9)
R10W (p.Arg10Trp) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
R10W (p.Arg10Trp) variant details
- p.Arg10Trp
- cosmic curated COSV61601
- gnomAD rs1283204100
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.20
- CADD 24.30
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available