P108L (p.Pro108Leu) variant of CASP9 (Caspase-9)
P108L (p.Pro108Leu) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P108L (p.Pro108Leu) variant details
- p.Pro108Leu
- 1000Genomes rs200310438
- TOPMed rs200310438
- gnomAD rs200310438
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.07
- CADD 17.20
- PolyPhen-2 0.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available