N105S (p.Asn105Ser) variant of CASP9 (Caspase-9)
N105S (p.Asn105Ser) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
N105S (p.Asn105Ser) variant details
- p.Asn105Ser
- ExAC rs775190388
- TOPMed rs775190388
- gnomAD rs775190388
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.08
- CADD 7.92
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available