N105D (p.Asn105Asp) variant of CASP9 (Caspase-9)
N105D (p.Asn105Asp) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
N105D (p.Asn105Asp) variant details
- p.Asn105Asp
- ExAC rs748635285
- TOPMed rs748635285
- gnomAD rs748635285
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.08
- CADD 5.43
- PolyPhen-2 0.06
- SIFT 1.00
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available