L20P (p.Leu20Pro) variant of CASP9 (Caspase-9)
L20P (p.Leu20Pro) in CASP9 (Caspase-9) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
L20P (p.Leu20Pro) variant details
- p.Leu20Pro
- 1000Genomes rs542382800
- ExAC rs542382800
- gnomAD rs542382800
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- REVEL 0.56
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available